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Duac

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  • Duac once daily 10mg/g + 50mg/g gel, 50g
  • Box of Duac Once Daily 50g gel
  • Duac once daily gel 50mg tube
  • Box of Duac gel and patient leaflet
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What is Duac?

Duac Once Daily gel is a topical acne treatment applied just once daily. It is effective against blackheads, whiteheads and pimples across the face and body.

It contains two active ingredients, which combine to target the acne bacteria and affect the skin cells. It takes around 2-5 weeks of treatment to work and it permanently improves your overall skin tone and texture.

It is a prescription-only treatment that can only be bought online at euroClinix with the approval of one of our online doctors.

How does Duac work?

Duac uses the active ingredients clindamycin phosphate and benzoyl peroxide.

graphic showing how the two ingredients of Duac gel work for acne.

These ingredients work together to target the acne bacteria and reduce skin inflammation.

  • Clindamycin phosphate is an antibiotic. It kills the bacteria that cause acne inflammation.
  • Benzoyl peroxide is an antiseptic and a common ingredient in acne treatments. It helps to break down the top layer of skin which unclogs your pores and reduces spots.

These ingredients help to reduce the appearance of acne as well as prevent future acne breakouts.

What are the benefits?

There are several benefits of using Duac for acne treatment:

  • Dual-action treatment - it contains two active ingredients that tackle multiple acne symptoms, which is more effective than most single-ingredient treatments.
  • Easy-to-use - you only have to apply it once a night before bedtime
  • Prevents acne flare-ups and acne scarring - meaning you won’t have to worry about your skin any longer.

This makes Duac an effective and simple-to-use acne treatment.

How effective is Duac for acne?

Research shows that Duac is a well-tolerated and effective treatment for acne.

Graph showing the effectiveness of different acne treatments

One study saw that after 11 weeks, 66% of patients using Duac Once Daily gel saw a reduction in their acne. This was compared to non-combination treatment and to those not using any treatment.

Who can use Duac?

Duac is safe to use for most adults with mild to moderate acne. If you have a medical condition or take any other medicine, talk to your doctor before using Duac.

Who cannot use Duac

Do not use Duac if you are allergic to clindamycin, benzoyl peroxide or any of the inactive ingredients.

Signs of an allergic reaction may include:

  • swelling of the face, eyes or lips
  • nettle rash
  • difficulty breathing
  • collapsing

Seek immediate medical attention if you experience any of these signs.

How do I use Duac?

To use Duac correctly, follow the dosage and treatment course our medical team prescribes. This ensures the medication’s effectiveness and helps avoid side effects.

When to use it

You should apply Duac once daily at night time. You should use it for a maximum of 12 weeks at a time unless otherwise advised.

How much should I use?

How much you should apply will depend on what areas are affected. Doses are measured in ‘fingertips’.

A ‘fingertip’ of gel is the amount of gel that spans the tip of your finger to the first joint (the first crease in your finger).

See the table below for how much you need to apply.

How much Duac gel you need to apply
Face 1 fingertip
Face & back 2 and a half fingertips

It should be applied as a thin film on your skin. If you are struggling to rub the gel into your skin, you may have applied too much.

Do not use too much gel. It will not improve acne recovery rates and may irritate your skin.

How to apply Duac:

  • Completely remove any make-up.
  • Wash the affected area of the skin well, rinse with warm water and pat dry.
  • Apply the correct amount of gel to all affected areas.
  • After applying, wash your hands.
  • Wait for it to dry completely before applying anything else on top.

Important notes:

  • Do not apply the gel to any irritated areas (e.g. if you have cuts, sunburn or broken skin).
  • Avoid contact with eyes, lips, mouth or inside your nose - if you apply Duac to any of these areas, rinse thoroughly with water.

You must use it properly and as prescribed. Stopping too soon may cause your acne to come back.

What happens if I miss a dose?

If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not take a double dose to make up for it.

How long does it take to work?

How long Duac will take to work will vary from person to person. Most people should see results in 2-5 weeks.

If you see no improvements after 12 weeks of using it, talk to your doctor or dermatologist for more advice.

What should I do whilst using Duac?

You should look after your skin while using Duac. Below are some skincare do’s and don’ts.

Do Don’t
  • Use a high-SPF sun cream every day.
  • Use gentle and hydrating skincare products.
  • Use a lip balm.
  • Use non-greasy makeup products.
  • Use harsh skincare products (e.g. chemical peels, chemical exfoliators or retinol).
  • Overuse Duac Gel.
  • Use greasy makeup products.

What are the side effects of Duac?

Like all prescription medicines, Duac gel may cause some side effects.

The most common side effects include:
  • headache
  • burning, pain or sensitivity after applying

These side effects are mild and should go away on their own once your body has adjusted to treatment.

If you experience too much irritation, you should use Duac less often or take a break from it for a few days. It may be from applying too much.

If the irritation is severe, stop treatment and talk to your doctor.

Uncommon side effects

Uncommon side effects affect fewer than 1 in every 100 people using this treatment.
  • pins and needles
  • worsening acne
  • itchy and red skin rash

Talk to your doctor if you experience any of these side effects and they do not go away.

Rare side effects

The following side effects are rare enough that their frequency is unknown. However, it’s still important you know them should they occur.
  • allergic reaction (e.g. swelling)
  • bloody diarrhoea or stomach pain caused by inflammation of the intestine
  • skin reaction or discolouration
  • raised itchy rash (hives)

Talk to your doctor if you experience any of these side effects or anything that is not listed. You can find a full list of side effects in the patient information leaflet here.

Does Duac interact with other medicines?

Always ask your doctor before starting Duac gel if you take any other medications as they may interact with each other.

Some products may cause irritation or additional side effects when used with Duac gel. This includes:

  • any other acne medications
  • chemical peels
  • medicated or harsh soaps and cleansers
  • soaps or cosmetics with a strong drying effect
  • products that tighten the skin (astringents)
  • certain antibiotics (e.g. dapsone or sulfacetamide)
  • salicylic acid

Duac gel can also affect the medicines used in general anaesthesia. Talk to your doctor first if you are due to have surgery before using this medicine.

It may also make other acne treatments less effective. This includes medicines that contain:

  • tretinoin (Treclin)
  • isotretinoin (Roaccutane)
  • tazarotene (Tazorac)

You can find a full list of potential drug interactions here.

What safety advice should be followed when using Duac?

Category Status Advice
Alcohol Safe It is safe to drink alcohol whilst using Duac.
Pregnancy Caution Consult your doctor before using it.
Breastfeeding Caution Consult your doctor before using it. If your doctor thinks it is safe to use, do not apply anywhere on the breast whilst breastfeeding.
Driving Safe Duac should not affect your ability to drive.

How do I store Duac gel?

Do not store Duac gel above 25°C. Keep it out of sight and reach of children. Once opened, discard after 2 months.

You should also not use it past the expiry date. You can see the expiry date on the medicine carton after EXP. The date refers to the last day of the month.

You should take any unused or expired Duac gel to a pharmacy to be disposed of. Do not dispose of it in the general waste or by flushing it down the toilet. This harms the environment.

Can I buy Duac without a prescription?

No, Duac Gel is a prescription-only medication. You need a valid prescription from a healthcare professional to purchase it. This ensures the medication is safe and suitable for your needs.

You can receive an online prescription from euroClinix.

How do I buy Duac online in the UK?

Ordering Duac Gel online from euroClinix is convenient.

Follow these simple steps:

  1. Complete a quick online consultation to check your eligibility.
  2. UK-registered doctors review your responses to ensure the medication is right for you.
  3. Upon approval, an e-prescription will be issued.
  4. Enjoy free delivery from our licensed pharmacy with tracking details.

Your privacy is our top priority. euroClinix uses secure, encrypted transactions and complies with UK medical standards to keep your information confidential.

Start your online consultation today to enjoy professional care from the comfort of your home.

Why should I choose euroClinix?

euroClinix is trusted by thousands of UK users for its safe and convenient service. Here’s why:

  • Experienced doctors manage your consultations and prescriptions.
  • Online consultations, quick approvals, and discreet doorstep delivery add to the convenience.
  • A supportive team is on hand to answer treatment-related questions or concerns.
  • Patients can manage their prescriptions hassle-free through our secure platform.

Join thousands who trust euroClinix for their healthcare needs and take control of your health today.

How much is Duac?

The price of Duac at euroClinix includes everything you need:

  • Free online consultation with our experienced doctors
  • Free prescription, if approved
  • Free delivery straight to your door

Our pricing is transparent, with no hidden fees. Order today and benefit from our complete, all-inclusive service.

What are the alternatives to Duac?

There are many different treatments available for acne. Alternatives include creams which have a thicker consistency than gels. Some alternatives may also be combined with oral antibiotics for more severe cases of acne.

Below are some common topical acne treatment alternatives to Duac.

Medicine Active ingredient Suitable for Combined with oral antibiotic* Price
Duac Once Daily Gel Benzoyl peroxide/ clindamycin phosphate Mild to moderate acne -
Differin Gel Adapalene Mild to moderate acne -
Epiduo gel Adapalene/ benzoyl peroxide Acne of any severity OR moderate to severe when used with an antibiotic -
Skinoren cream Azelaic acid Mild to moderate acne OR moderate to severe when used with an antibiotic -
Treclin gel Tretinoin/ benzoyl peroxide Acne of any severity -

*Can be taken with the oral antibiotics Lymecycline or Doxycycline.

Duac FAQs

Is Duac a steroid cream?
Does Duac help acne scars?
Does Duac treat rosacea?
How long do you leave Duac gel on your face?
Do you wash Duac off in the morning?
Does Duac cause purging?
What happens if I stop using Duac?
Is Duac gel safe?
Are there any discounts for new users?
Is it safe to buy Duac online?
Will my order be confidential?

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Caroline Fontana Written by our editorial team Last reviewed 19-11-2024
Duac information
Group of medication Antibiotics/antiseptics
Used for Acne
Active ingredient(s) Clindamycin & benzoyl peroxide
Works by Killing the acne bacteria
Effective within 2-5 weeks
Suitable for Adults with mild to moderate acne
Available as Gel
Available strength 1% Clindamycin & 5% Benzoyl peroxide
Dosage instructions Apply once daily in the evening for a maximum of 12 weeks at a time.
Manufacturer GlaxoSmithKline UK
Generic available No
Storage Do not store above 25°C and discontinue use after the expiry date.
Prescription required Yes - included with our free online consultation.
Duac reviews
Duac once daily 10mg/g + 50mg/g gel, 50g Excellent 4.6 16 patients have reviewed Duac on Trustpilot
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